Sitagen-M Tablet 50/500mg is a combination antidiabetic medicine containing Sitagliptin 50mg and Metformin 500mg. It is prescribed for the management of Type 2 Diabetes Mellitus in adults when diet, exercise, or a single medication alone is not enough to control blood sugar levels. The combination works through two different mechanisms to improve glycemic control and reduce the risk of diabetes-related complications.

Sitagen-M helps lower blood glucose levels by improving insulin secretion, reducing glucose production in the liver, and increasing the body's sensitivity to insulin. It is commonly used as part of a comprehensive diabetes management plan that includes a healthy diet and regular physical activity.

Uses

• Management of Type 2 Diabetes Mellitus
• Improving blood sugar control in adults
• Reducing fasting and post-meal blood glucose levels
• Used when monotherapy is insufficient for diabetes control
• Supporting long-term diabetes management alongside diet and exercise

Benefits

• Provides dual-action blood sugar control
• Helps improve insulin sensitivity
• Reduces glucose production by the liver
• Supports better HbA1c management
• Convenient combination therapy in a single tablet
• May help reduce the risk of diabetes-related complications when used regularly as prescribed

Dosage

• Take exactly as prescribed by your healthcare professional
• Usually taken once or twice daily with meals
• Swallow the tablet whole with water
• Do not skip doses or discontinue treatment without medical advice
• Follow dietary and exercise recommendations for best results

Prescription Required: Yes.

How It Works

Metformin decreases glucose production in the liver, reduces intestinal glucose absorption, and improves insulin sensitivity. Sitagliptin is a DPP-4 inhibitor that increases incretin hormone activity, helping the pancreas release more insulin when blood sugar levels are high and reducing glucagon production. Together, they provide effective blood sugar control in patients with Type 2 Diabetes.

Common Side Effects

• Nausea
• Diarrhea
• Stomach discomfort
• Headache
• Dizziness
• Loss of appetite
• Upper respiratory tract infections
• Low blood sugar (especially when combined with other diabetes medicines)

Do Not Use If

• You are allergic to Sitagliptin, Metformin, or any of the ingredients
• You have Type 1 Diabetes Mellitus
• You have diabetic ketoacidosis
• You have severe kidney impairment
• You have severe liver disease unless advised by a doctor
• The medication has not been prescribed by a qualified healthcare professional

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children.

Price in Pakistan

The price of Sitagen-M Tablet 50/500mg (30 tablets) in Pakistan generally ranges between Rs. 1,050 and Rs. 1,250, depending on the pharmacy, location, and availability.

FAQs

Q1: What is Sitagen-M Tablet 50/500mg used for?

It is used to manage Type 2 Diabetes Mellitus and help control blood sugar levels when lifestyle changes or a single medication are not sufficient.

Q2: Should Sitagen-M be taken with food?

Yes, it is usually recommended to take Sitagen-M with meals to reduce stomach-related side effects associated with Metformin.

Q3: Can Sitagen-M cure diabetes?

No. Sitagen-M helps manage blood sugar levels but does not cure diabetes. Long-term treatment and lifestyle modifications are typically required.

Q4: What should I do if I miss a dose?

Take the missed dose as soon as you remember unless it is almost time for your next dose. Do not take a double dose to make up for a missed one.

Q5: Is Sitagen-M Tablet 50/500mg a prescription medicine?

Yes. Sitagen-M is a prescription-only medication and should be used under the supervision of a healthcare professional.