Sacvalz 50mg Tablet is a combination medicine containing Sacubitril + Valsartan, classified as an ARNI (Angiotensin Receptor–Neprilysin Inhibitor). It is mainly used for the long-term management of chronic heart failure (HFrEF).

This medicine works by relaxing blood vessels, reducing fluid retention, and improving the heart’s ability to pump blood efficiently. It also helps reduce the risk of hospitalization and cardiovascular death in heart failure patients.

Uses of Sacvalz 50mg Tablet

• Chronic heart failure (HFrEF)
• Reduced ejection fraction heart failure
• Blood pressure management (in selected patients)
• Prevention of heart failure worsening
• Reducing risk of hospitalization due to heart conditions

Benefits

• Improves heart pumping efficiency
• Lowers strain on the heart
• Reduces blood pressure
• Decreases risk of heart failure hospitalization
• Improves exercise tolerance and quality of life
• Supports long-term heart health

How It Works

Sacubitril increases beneficial peptides that relax blood vessels and remove excess fluid from the body. Valsartan blocks angiotensin II receptors, which reduces blood vessel narrowing and lowers blood pressure. Together, they improve heart function and reduce cardiac stress.

Dosage

• Usually 1 tablet twice daily (as prescribed by a cardiologist)
• Can be taken with or without food
• Dose is adjusted based on blood pressure and kidney function
• Do not stop suddenly without medical advice

Price in Pakistan

Approximate price:

• PKR 330 – PKR 750 per strip (14 tablets) depending on brand, pharmacy, and city (e.g., Sacvalz/Sacuvia/Sacvin equivalents vary widely)

Possible Side Effects

• Dizziness
• Low blood pressure
• High potassium levels
• Fatigue
• Kidney function changes
• Cough (less common than ACE inhibitors)

Do Not Use If

• You are allergic to Sacubitril or Valsartan
• You are pregnant
• You have severe liver disease without doctor supervision
• You are using ACE inhibitors (without proper washout period)
• You have very low blood pressure

Storage

Store below 25–30°C in a dry place away from sunlight and moisture. Keep out of reach of children.

FAQs

Q1: What is Sacvalz 50mg used for?

It is mainly used to treat chronic heart failure and improve heart function.

Q2: Does it lower blood pressure?

Yes, it helps reduce blood pressure in patients with heart-related conditions.

Q3: How long does it take to work?

It starts working within hours, but full heart benefits develop over weeks.

Q4: Is it safe long term?

Yes, but only under regular monitoring by a cardiologist.