Sitaglu Met XR 100+1000mg Tablet contains sitagliptin 100mg and metformin hydrochloride 1000mg extended-release. It is a combination antidiabetic medicine used with diet and exercise to improve blood glucose control in adults with type 2 diabetes.

Sitagliptin is a DPP-4 inhibitor that helps the body release more insulin when blood sugar is elevated and reduces the release of glucagon. Metformin reduces glucose production by the liver and improves insulin sensitivity. Together, these medicines help maintain better blood glucose control.

Uses

• Helps control blood sugar in adults with type 2 diabetes
• Used alongside diet and regular physical activity
• May be prescribed when combination therapy with sitagliptin and metformin is appropriate
• Helps improve overall glycemic control
• May help reduce blood glucose levels over the course of treatment

Benefits

• Combines two complementary diabetes medicines
• Helps improve blood glucose control
• Supports better insulin response after meals
• Reduces excessive glucose production by the liver
• Extended-release metformin provides prolonged drug release
• Convenient combination tablet

Dosage

• Take Sitaglu Met XR 100+1000mg exactly as prescribed by your doctor.
• It is generally taken once daily with a meal, depending on the prescribed regimen.
• Swallow the extended-release tablet whole with water.
• Do not crush, split, or chew the tablet unless specifically instructed.
• The appropriate dose depends on blood glucose control, previous treatment, and kidney function.
• Monitor blood glucose according to your healthcare professional's recommendations.
• Do not change the dose or stop treatment without medical advice.

Possible Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Abdominal discomfort
• Headache
• Indigestion
• Nasal congestion or sore throat

Rarely, metformin can cause lactic acidosis, a serious condition. Seek urgent medical attention for severe weakness, unusual muscle pain, difficulty breathing, persistent vomiting, abdominal discomfort, or unusual sleepiness.

Precautions

• Tell your doctor if you have kidney disease, liver disease, heart failure, or a history of pancreatitis.
• Kidney function should be checked before and during treatment as recommended.
• Avoid excessive alcohol consumption because it may increase the risk of lactic acidosis.
• Inform your doctor before undergoing an imaging procedure involving iodinated contrast dye, as metformin may need to be temporarily withheld.
• Contact your doctor promptly if you develop persistent severe abdominal pain, especially if it radiates to the back.
• The risk of hypoglycemia may increase when this medicine is combined with insulin or sulfonylureas.
• Tell your doctor about all medicines, vitamins, and supplements you use.

FAQs

Q1: What is Sitaglu Met XR 100+1000mg Tablet used for?

It contains sitagliptin 100mg and extended-release metformin 1000mg and is used with diet and exercise to improve blood glucose control in adults with type 2 diabetes.

Q2: What does XR mean in Sitaglu Met XR?

XR means extended release. The metformin component is formulated to release gradually over time.

Q3: Should Sitaglu Met XR 100+1000mg be taken with food?

Yes. It is generally taken with a meal, which can also help reduce gastrointestinal side effects from metformin.

Q4: Can I crush or chew Sitaglu Met XR?

No. Extended-release tablets should generally be swallowed whole to preserve the intended release characteristics.

Q5: Can Sitaglu Met XR cause low blood sugar?

Sitagliptin and metformin have a relatively low risk of hypoglycemia when used alone. The risk can increase when used with insulin or sulfonylureas.

Q6: Can Sitaglu Met XR be used for type 1 diabetes?

No. This combination is intended for adults with type 2 diabetes and does not replace insulin therapy for type 1 diabetes.