Sitagliptin is a DPP-4 inhibitor that helps increase insulin release when blood glucose is elevated and reduces glucagon levels. Metformin decreases glucose production by the liver and improves the body's sensitivity to insulin. Together, they help maintain better blood sugar control.
Uses
- Helps control blood sugar in adults with type 2 diabetes
- Used alongside a healthy diet and regular exercise
- May be prescribed when metformin alone does not provide adequate glucose control
- Helps improve overall glycemic control
- May be used as part of combination diabetes treatment
Benefits
- Combines sitagliptin and metformin in one tablet
- Helps lower elevated blood glucose levels
- Supports insulin release when blood sugar is high
- Helps reduce glucose production by the liver
- Improves the body's response to insulin
- Convenient combination formulation
Dosage
- Take Sitaglu Met 50mg+850mg exactly as prescribed by your doctor.
- It is generally taken with meals to reduce stomach-related side effects associated with metformin.
- Swallow the tablet with water.
- The dose and frequency depend on blood glucose control, kidney function, and previous diabetes treatment.
- Monitor blood glucose as advised by your healthcare professional.
- Do not change the dose or stop treatment without medical advice.
Possible Side Effects
Common side effects may include:
- Nausea
- Diarrhea
- Abdominal discomfort
- Indigestion
- Headache
- Nasal congestion or sore throat
Rarely, metformin can cause lactic acidosis, particularly in people with significant kidney impairment or other risk factors. Seek urgent medical attention for severe weakness, unusual muscle pain, difficulty breathing, persistent vomiting, or unusual sleepiness.
Precautions
- Tell your doctor if you have kidney disease, liver disease, heart failure, or a history of pancreatitis.
- Kidney function should be assessed before and during treatment as recommended.
- Avoid excessive alcohol consumption because it can increase the risk of metformin-associated lactic acidosis.
- Inform your doctor before an imaging procedure involving iodinated contrast dye, as metformin may need to be temporarily withheld.
- Seek medical advice for persistent or severe abdominal pain, especially if it radiates to the back.
- The risk of low blood sugar may increase when used with insulin or sulfonylureas.
- Inform your doctor about all medicines, vitamins, and supplements you take.
FAQs
Q1: What is Sitaglu Met 50mg+850mg Tablet used for?
It contains sitagliptin 50mg and metformin 850mg and is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.
Q2: Should Sitaglu Met 50mg+850mg be taken with food?
Yes. Taking it with meals can help reduce stomach-related side effects associated with metformin.
Q3: Can Sitaglu Met cause low blood sugar?
Sitagliptin and metformin have a relatively low risk of hypoglycemia when used alone. The risk can increase when combined with insulin or sulfonylureas.
Q4: Can people with kidney problems take Sitaglu Met?
The suitability and dose depend on kidney function. Your doctor should assess kidney function before prescribing and during treatment when appropriate.
Q5: Can Sitaglu Met be used for type 1 diabetes?
No. This combination is intended for adults with type 2 diabetes and does not replace insulin therapy for type 1 diabetes.
Q6: What should I do if I miss a dose?
Take the missed dose when you remember, preferably with food, unless it is close to the next scheduled dose. Do not take two doses together.
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