Sacubitril enhances the body's natural protective peptides, promoting blood vessel relaxation and sodium excretion, while Valsartan blocks the effects of angiotensin II, helping to lower blood pressure and reduce strain on the heart. Together, they improve the heart's ability to pump blood more effectively.

Uses

• Treatment of chronic heart failure with reduced ejection fraction (HFrEF)
• Reduces the risk of hospitalization due to heart failure
• Helps lower the risk of cardiovascular death in eligible patients
• Improves symptoms such as shortness of breath and fatigue
• Enhances exercise tolerance and quality of life in patients with heart failure

Benefits

• Improves heart function
• Helps reduce symptoms of chronic heart failure
• Lowers the risk of heart failure-related hospitalization
• Helps decrease cardiovascular mortality
• Combines two proven heart failure medicines in one tablet
• Convenient twice-daily dosing as prescribed by your healthcare professional

Dosage

• Take exactly as prescribed by your healthcare professional.
• Swallow the tablet whole with water.
• It may be taken with or without food.
• Take it at the same times each day for the best results.
• Do not stop taking the medicine without consulting your doctor.
• If switching from an ACE inhibitor, allow a 36-hour washout period before starting Savesto to reduce the risk of angioedema.

Prescription Required: Yes.

How It Works

Sacubitril inhibits the neprilysin enzyme, increasing beneficial natriuretic peptides that promote vasodilation, sodium excretion, and reduced cardiac workload. Valsartan blocks angiotensin II receptors, relaxing blood vessels, lowering blood pressure, and reducing stress on the heart. Together, they improve heart function and slow the progression of heart failure.

Common Side Effects

• Low blood pressure (hypotension)
• Dizziness
• Increased blood potassium levels
• Reduced kidney function
• Cough
• Fatigue

Seek immediate medical attention if you develop swelling of the face, lips, tongue, or throat (angioedema).

Do Not Use If

Do not use Savesto 50 Tablet if:

• You are allergic to Sacubitril, Valsartan, or any of the ingredients.
• You have a history of angioedema related to ACE inhibitors or ARBs.
• You are taking an ACE inhibitor without the required 36-hour washout period.
• You are pregnant, especially during the second or third trimester.
• You have severe liver impairment unless advised by your healthcare provider.
• The medicine has not been prescribed by a qualified healthcare professional.

Frequently Asked Questions (FAQs)

Q1: What is Savesto 50 Tablet used for?

Savesto 50 Tablet is used to treat chronic heart failure with reduced ejection fraction (HFrEF). It helps improve heart function and reduces the risk of hospitalization and cardiovascular death.

Q2: Can Savesto 50 Tablet be taken with food?

Yes. Savesto can be taken with or without food. Take it consistently as directed by your healthcare professional.

Q3: Can I stop taking Savesto if I feel better?

No. Heart failure is a long-term condition. Continue taking Savesto exactly as prescribed unless your doctor advises otherwise.

Q4: Does Savesto lower blood pressure?

Yes. Savesto may lower blood pressure as part of its therapeutic effect, so your doctor may monitor your blood pressure regularly during treatment.

Q5: Is a prescription required for Savesto 50 Tablet?

Yes. Savesto 50 Tablet is a prescription-only medicine and should only be used under the supervision of a qualified healthcare professional.