Savesto 100 Tablet 49mg/51mg contains Sacubitril and Valsartan, a combination medicine used to treat chronic heart failure in adults. It helps the heart pump blood more effectively and reduces the risk of hospitalization and cardiovascular complications.

Sacubitril works by inhibiting the enzyme neprilysin, which increases beneficial peptides that relax blood vessels and reduce fluid buildup. Valsartan is an angiotensin receptor blocker (ARB) that lowers blood pressure and reduces strain on the heart. Together they improve heart efficiency and circulation.

Savesto is commonly prescribed for patients with symptomatic chronic heart failure with reduced ejection fraction (HFrEF) and is usually used along with other heart-failure medicines under medical supervision.

Price in Pakistan

The approximate price of Savesto 100 Tablet 49mg/51mg (14 tablets pack) in Pakistan is around Rs. 780 – Rs. 888, depending on the pharmacy and city.

Uses

• Treatment of chronic heart failure (HFrEF)

• Helps improve heart pumping function

• Reduces risk of hospitalization for heart failure

• Lowers blood pressure and heart strain

• Supports long-term cardiovascular management

Benefits

• Improves heart efficiency and circulation

• Helps reduce symptoms like shortness of breath and fatigue

• Lowers the risk of heart failure complications

• Combines two effective heart medicines in one tablet

• Supports better long-term heart health

Prescription Required: Yes

Generic Name: Sacubitril / Valsartan

Use: Treatment of chronic heart failure

How It Works

• Sacubitril: Blocks neprilysin, increasing beneficial peptides that relax blood vessels and remove excess sodium and fluid.

• Valsartan: Blocks angiotensin II receptors, reducing blood pressure and decreasing strain on the heart.

Together they improve heart function and circulation.

Dosage

• Usually 1 tablet twice daily or as prescribed by a doctor.

• Can be taken with or without food.

• Dose may be adjusted based on blood pressure and kidney function.

Common Side Effects

• Low blood pressure (hypotension)

• Dizziness

• Increased potassium levels

• Kidney function changes

• Cough or fatigue

Drug Interactions

• ACE inhibitors

• Other blood pressure medicines

• Potassium supplements

• Diuretics

• NSAIDs

Do Not Use If

• Allergy to Sacubitril or Valsartan

• History of angioedema with ACE inhibitors

• Severe liver disease

• Pregnancy (may harm the unborn baby)

Storage

Store at room temperature below 30°C, away from moisture and direct sunlight. Keep out of reach of children.

FAQs

Q1: What is Savesto 100 Tablet used for?

It is used to treat chronic heart failure and improve heart function.

Q2: How often should Savesto be taken?

Usually twice daily, but follow your doctor’s instructions.

Q3: Can Savesto reduce hospitalizations?

Yes, it helps lower the risk of heart failure-related hospital admissions.

Q4: Can it be taken with other heart medicines?

Yes, but only under doctor supervision.

Q5: Does Savesto lower blood pressure?

Yes, it helps relax blood vessels and reduce blood pressure.

Q6: Is Savesto a lifelong medicine?

Many heart failure patients take it long-term under medical guidance.

Q7: Can pregnant women take Savesto?

No, it should not be used during pregnancy.