Gliptin Plus 50/500mg Tablet is a combination antidiabetic medicine containing Sitagliptin 50mg and Metformin Hydrochloride 500mg. It is prescribed for the treatment of Type 2 Diabetes Mellitus in adults when diet, exercise, and single-drug therapy are not sufficient to control blood sugar levels. The combination helps improve glycemic control through complementary mechanisms and may reduce the risk of long-term diabetes-related complications.

Sitagliptin belongs to the DPP-4 inhibitor class, which increases insulin release and reduces glucagon production after meals. Metformin decreases glucose production in the liver and improves insulin sensitivity, helping the body use insulin more effectively.

Uses

• Management of Type 2 Diabetes Mellitus
• Blood sugar control alongside diet and exercise
• Combination therapy for patients requiring Sitagliptin and Metformin
• Prevention of diabetes-related complications through improved glycemic control

Benefits

• Helps lower fasting and post-meal blood glucose levels
• Improves insulin sensitivity
• Reduces glucose production by the liver
• Supports long-term diabetes management
• Convenient combination of two effective antidiabetic medicines in one tablet
• May help reduce the risk of diabetes-related complications when used regularly as prescribed

Dosage

• Take exactly as prescribed by your doctor
• Usually taken once or twice daily with meals
• Swallow the tablet whole with water
• Follow a healthy diet and exercise program during treatment
• Do not adjust the dose without medical advice

Prescription Required

Yes. S Gliptin Plus 50/500mg Tablet is a prescription-only medication.

How It Works

Sitagliptin inhibits the DPP-4 enzyme, increasing incretin hormone levels that stimulate insulin release and reduce glucagon secretion. Metformin reduces glucose production in the liver and improves the body's response to insulin. Together, these actions help maintain healthy blood sugar levels in patients with Type 2 diabetes.

Common Side Effects

• Nausea
• Vomiting
• Diarrhea
• Stomach upset
• Headache
• Weakness
• Metallic taste in the mouth
• Abdominal discomfort

Do Not Use If

• You are allergic to Sitagliptin, Metformin, or any ingredient in the tablet
• You have severe kidney disease
• You have diabetic ketoacidosis
• You have severe liver impairment unless advised by a doctor
• The medicine has not been prescribed by a healthcare professional

Precautions

• Use with caution in patients with kidney or liver disease
• Inform your doctor if you have a history of pancreatitis or gallstones
• Regular monitoring of blood glucose and kidney function may be required
• Avoid excessive alcohol consumption while taking this medicine

Storage Instructions

Store below 30°C in a cool, dry place away from direct sunlight and moisture. Keep out of the reach of children.

Price in Pakistan

The price of S Gliptin Plus 50/500mg Tablet 14's may vary by pharmacy and location. Recent online listings show prices ranging from approximately Rs. 260 to Rs. 550 per pack of 14 tablets.

Frequently Asked Questions (FAQs)

Q1: What is S Gliptin Plus 50/500mg Tablet used for?

It is used to improve blood sugar control in adults with Type 2 Diabetes Mellitus.

Q2: What are the active ingredients in S Gliptin Plus?

Each tablet contains Sitagliptin 50mg and Metformin Hydrochloride 500mg.

Q3: Should S Gliptin Plus be taken with food?

Yes, it is generally recommended to take the tablet with meals to reduce stomach-related side effects associated with Metformin.

Q4: Can S Gliptin Plus cure diabetes?

No. It helps manage blood sugar levels but does not cure diabetes. A healthy diet, regular exercise, and medical follow-up remain important.

Q5: Is a prescription required for S Gliptin Plus 50/500mg?

Yes. This medicine should only be used under the supervision of a qualified healthcare professional.