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Composition

• Each tablet contains:
• Sevelamer – 400 mg

Therapeutic Class

• Phosphate Binder

Indication

• Renavel 400 mg Tablet is used to control high phosphate levels (hyperphosphatemia) in patients with chronic kidney disease (CKD), especially those undergoing dialysis.

Mechanism of Action

• Sevelamer is a non-absorbed phosphate binder. It works by binding dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. This helps maintain normal phosphate levels and reduces complications related to mineral and bone disorders in kidney disease.

Dosage & Administration

• • The dosage is as prescribed by the physician

  • Usually taken with meals

  • Tablets should be swallowed whole and not crushed or chewed

Benefits

• • Effectively reduces serum phosphate levels

  • Helps prevent bone disorders in CKD patients

  • Does not contain calcium or aluminum

  • Suitable for long-term use under medical supervision

Side Effects

Common side effects may include:

• • Nausea

  • Vomiting

  • Constipation

  • Diarrhea

  • Abdominal pain

Most side effects are mild and temporary.

Precautions & Warnings

• • Use with caution in patients with bowel obstruction or severe constipation

  • Regular monitoring of phosphate levels is recommended

  • Inform the doctor about all other medications being taken

Storage Instructions

• • Store in a cool, dry place

  • Protect from moisture

  • Keep out of reach of children

Alternative Brands (Same Active Ingredient – Sevelamer)

Renavel 400 mg Tablet can be substituted with the following alternatives (as advised by a doctor):

• • Sevphos

  • Sevla

  • Sevelawin

All these brands contain Sevelamer and are used for the same indication.