Velso 100/400mg Tablets contain a fixed-dose combination of Sofosbuvir 400mg and Velpatasvir 100mg. It is a direct-acting antiviral medicine used for the treatment of chronic Hepatitis C virus (HCV) infection in adults.

Sofosbuvir and Velpatasvir work together by targeting different stages of the Hepatitis C virus life cycle, helping prevent viral replication and supporting clearance of the infection. This combination is active against multiple Hepatitis C genotypes when prescribed according to medical guidelines.

Uses

• Treatment of chronic Hepatitis C (HCV) infection
• Management of Hepatitis C genotypes 1–6 when prescribed
• Treatment of HCV infection in adults under specialist supervision
• May be used in patients with liver disease according to a doctor's assessment

Benefits

• Helps reduce Hepatitis C virus levels in the body
• Targets viral replication through two different mechanisms
• Convenient once-daily tablet regimen
• May help prevent further liver damage caused by chronic HCV infection
• Effective antiviral combination therapy when used appropriately

Dosage

• Take Velso 100/400mg Tablet exactly as prescribed by your hepatologist or healthcare provider.
• The usual regimen is one tablet once daily, but duration depends on the patient's condition, HCV genotype, and liver status.
• Swallow the tablet whole with water.
• It may be taken with or without food.
• Complete the full treatment course even if you feel better.

Prescription Required: Yes.

How It Works

Velso contains two direct-acting antiviral medicines:

• Sofosbuvir: Blocks the HCV NS5B polymerase enzyme, which is essential for viral replication.
• Velpatasvir: Blocks the HCV NS5A protein involved in viral replication and assembly.

Together, they stop the Hepatitis C virus from multiplying and help the body clear the infection.

Common Side Effects

• Headache
• Fatigue
• Nausea
• Weakness
• Insomnia
• Diarrhea

Consult your doctor if side effects become severe or persistent.

Do Not Use If

• You are allergic to Sofosbuvir, Velpatasvir, or any ingredient in the tablet.
• You are taking medicines that may interact with Sofosbuvir/Velpatasvir.
• You have severe liver problems unless monitored by a specialist.
• The medicine has not been prescribed by a qualified healthcare professional.

Drug Interactions

Inform your doctor if you are using:

• Certain acid-reducing medicines (such as some antacids or proton pump inhibitors)
• Amiodarone or medicines affecting heart rhythm
• Other antiviral medicines
• Herbal supplements such as St. John’s wort

Storage Instructions

• Store below 30°C in a cool, dry place.
• Protect from moisture and direct sunlight.
• Keep out of reach of children.

Price in Pakistan

The price of Velso 100/400mg Tablets (28 tablets pack) in Pakistan generally ranges from approximately Rs. 10,000 to Rs. 15,600, depending on the pharmacy, availability, and location.

Frequently Asked Questions (FAQs)

Q1: What is Velso 100/400mg Tablet used for?

Velso is used to treat chronic Hepatitis C virus infection by reducing viral replication and helping clear the infection.

Q2: What are the ingredients in Velso Tablet?

Each tablet contains Sofosbuvir 400mg and Velpatasvir 100mg.

Q3: How long does Velso treatment take?

Treatment duration varies depending on the patient's HCV genotype, liver condition, and previous treatment history. Follow your doctor's prescribed course.

Q4: Can Velso Tablet cure Hepatitis C?

Velso can help achieve viral clearance in many patients when used correctly under medical supervision, but treatment response depends on individual health factors.

Q5: Is a prescription required for Velso 100/400mg Tablet?

Yes. Velso is a prescription antiviral medicine and should only be used under the supervision of a qualified healthcare professional.