Glytec-M XR 50mg/500mg Tablet is a combination antidiabetic medicine containing Sitagliptin 50mg and Metformin Hydrochloride Extended-Release (XR) 500mg. It is used to improve blood sugar control in adults with type 2 diabetes mellitus when combined with a healthy diet and regular exercise.

Sitagliptin increases the body's natural insulin release after meals and reduces glucose production, while Metformin XR decreases glucose production in the liver and improves the body's sensitivity to insulin. Together, they help maintain stable blood glucose levels throughout the day.

Uses

• Management of type 2 diabetes mellitus
• Improvement of blood glucose control alongside diet and exercise
• Reduction of HbA1c levels
• Suitable for patients requiring combination therapy with Sitagliptin and Metformin XR

Benefits

• Provides dual-action blood sugar control
• Helps lower fasting and post-meal blood glucose levels
• Extended-release formulation for prolonged glucose control
• Improves insulin sensitivity
• Convenient once-daily dosing when prescribed
• May reduce the risk of diabetes-related complications through improved glycemic control

Dosage

• Take Glytec-M XR exactly as prescribed by your healthcare provider.
• Usually taken once daily with a meal to reduce stomach upset.
• Swallow the tablet whole with water; do not crush, chew, or split the tablet.
• Continue following your recommended diet, exercise, and blood glucose monitoring plan while taking this medicine.

Prescription Required: Yes.

How It Works

Glytec-M XR combines two medicines with complementary actions:

• Sitagliptin is a DPP-4 inhibitor that increases incretin hormone levels, stimulating insulin release and reducing glucagon secretion after meals.
• Metformin XR reduces glucose production by the liver, decreases intestinal glucose absorption, and improves insulin sensitivity.

Together, they help achieve better long-term blood sugar control in adults with type 2 diabetes.

Common Side Effects

• Nausea
• Diarrhea
• Stomach discomfort
• Headache
• Bloating
• Upper respiratory symptoms
• Low blood sugar (more likely when combined with insulin or sulfonylureas)
• Vitamin B12 deficiency with long-term Metformin use

Most side effects are mild and temporary. Contact your healthcare provider if symptoms persist or if you experience severe abdominal pain, difficulty breathing, or signs of lactic acidosis.

FAQs

Q1: What is Glytec-M XR 50mg/500mg Tablet used for?

Glytec-M XR is used to improve blood sugar control in adults with type 2 diabetes mellitus, alongside diet and exercise.

Q2: Should Glytec-M XR be taken with food?

Yes. It is generally recommended to take Glytec-M XR with a meal to help reduce stomach-related side effects.

Q3: Can Glytec-M XR be used for type 1 diabetes?

No. Glytec-M XR is indicated for the management of type 2 diabetes mellitus and is not intended for treating type 1 diabetes or diabetic ketoacidosis.

Q4: Can Glytec-M XR cause low blood sugar?

The risk of hypoglycemia is generally low when used alone, but it may increase if taken with insulin or certain other diabetes medicines.

Q5: Is a prescription required for Glytec-M XR 50mg/500mg Tablet?

Yes. Glytec-M XR is a prescription-only medicine and should be used under the supervision of a qualified healthcare professional