Glucophage XR 750mg Tablet is an extended-release formulation of Metformin Hydrochloride 750mg, manufactured by Martin Dow Pharmaceuticals in Pakistan. It is an oral antidiabetic medicine primarily used to improve blood glucose control in adults with type 2 diabetes mellitus. Pakistani pharmacy listings commonly show a 30-tablet pack (3 × 10).

Metformin works mainly by reducing glucose production by the liver and improving the body's sensitivity to insulin, helping the body use glucose more effectively. The XR formulation is designed for prolonged release and convenient dosing.

Uses

• Management of Type 2 Diabetes
• Helps control high blood sugar
• Used alongside a healthy diet and regular exercise
• May be used alone or with other diabetes medicines
• May be prescribed with insulin when additional blood-glucose control is needed

Glucophage XR is also used in some settings for adults with certain high-risk prediabetes profiles and for PCOS-related ovulation management, but these uses should be determined by a physician.

Benefits

• Helps lower elevated blood glucose
• Reduces glucose production by the liver
• Improves insulin sensitivity
• Supports better glucose utilization by body tissues
• Extended-release formulation provides prolonged drug release
• Convenient dosing for long-term diabetes management

Composition

Each Glucophage XR 750mg Tablet contains:

• Metformin Hydrochloride 750mg

It belongs to the biguanide class of oral antidiabetic medicines.

Dosage

• Take Glucophage XR 750mg exactly as prescribed by your doctor.
• It is generally taken with or after a meal to improve gastrointestinal tolerance.
• Swallow the XR tablet whole with water.
• Do not crush, chew or split the extended-release tablet unless specifically instructed.
• Your doctor determines the dose according to your blood glucose levels, kidney function and response to treatment.

Possible Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Vomiting
• Stomach discomfort
• Abdominal pain
• Bloating
• Loss of appetite
• Metallic taste
• Weakness

Long-term metformin treatment can sometimes be associated with Vitamin B12 deficiency.

A very rare but serious complication is lactic acidosis, particularly in people with significant kidney impairment or certain other risk factors.

Precautions

• Tell your doctor if you have kidney or liver disease.
• Kidney function should be assessed before and during treatment when appropriate.
• Avoid excessive alcohol consumption.
• Tell your doctor before undergoing an imaging procedure involving iodinated contrast, as metformin may need to be temporarily stopped.
• Inform your doctor about all medicines and supplements you use.
• Monitor your blood glucose as recommended.
• Do not change your dose without medical advice.
• Seek urgent medical attention for severe weakness, difficulty breathing, persistent vomiting, unusual sleepiness or severe abdominal discomfort.

Price in Pakistan

The price of Glucophage XR 750mg varies by pharmacy, pack size and current pricing. Recent Pakistani listings show different retail prices, including approximately Rs. 204 for a 30-tablet pack at Servaid and other listings ranging from around Rs. 369–451 depending on seller and presentation. Always verify the current price before publishing a fixed price on your website.

FAQs

Q1: What is Glucophage XR 750mg used for?

It is primarily used to help control blood sugar in people with Type 2 Diabetes.

Q2: What is the active ingredient in Glucophage XR 750mg?

It contains Metformin Hydrochloride 750mg.

Q3: What does XR mean?

XR means extended release, meaning the medicine is formulated to release metformin gradually.

Q4: Can Glucophage XR 750mg be used for diabetes with insulin?

Yes. It may be prescribed together with insulin when additional blood-sugar control is required.

Q5: Can Glucophage XR 750mg cause low blood sugar?

Metformin alone generally has a low risk of hypoglycemia. However, low blood sugar can become more likely when it is combined with insulin or certain other diabetes medicines.