Esso-NS 375/20 Tablet contains a combination of naproxen sodium 375mg and esomeprazole 20mg. It is used to manage pain and inflammation, particularly when an NSAID is required in patients who also need protection against NSAID-associated stomach irritation.

Naproxen sodium is a non-steroidal anti-inflammatory drug (NSAID) that helps reduce pain, swelling, and inflammation. Esomeprazole is a proton-pump inhibitor (PPI) that reduces stomach acid and helps lower the risk of certain NSAID-related upper gastrointestinal problems.

Uses

• Helps relieve pain and inflammation
• Used for symptoms associated with arthritis
• May help relieve joint pain, swelling, and stiffness
• Helps reduce stomach-acid-related irritation associated with NSAID treatment
• May be prescribed when an anti-inflammatory medicine is needed with gastrointestinal protection

Benefits

• Combines an NSAID with an acid-reducing medicine
• Helps reduce pain and inflammation
• May improve comfort and mobility in inflammatory joint conditions
• Helps reduce the risk of some NSAID-related stomach problems
• Convenient combination tablet formulation

Dosage

• Take Esso-NS 375/20 Tablet exactly as prescribed by your doctor.
• The dose and duration depend on your medical condition and response to treatment.
• Swallow the tablet whole with water.
• Do not crush, chew, or split the tablet unless your doctor or pharmacist specifically instructs you to do so.
• Take it with or after food if recommended to reduce stomach discomfort.
• Do not take additional NSAIDs such as ibuprofen, diclofenac, or naproxen unless advised by your doctor.
• Do not exceed the prescribed dose or duration.

Possible Side Effects

Some people may experience:

• Indigestion
• Nausea
• Stomach discomfort
• Diarrhea or constipation
• Headache
• Dizziness
• Abdominal pain

Naproxen can rarely cause stomach ulcers or bleeding, kidney problems, cardiovascular complications, or serious allergic reactions. Seek urgent medical attention for vomiting blood, black stools, severe chest pain, difficulty breathing, facial swelling, or significantly reduced urination.

Precautions

• Tell your doctor if you have stomach ulcers, gastrointestinal bleeding, kidney disease, liver disease, heart disease, high blood pressure, or asthma triggered by NSAIDs.
• Do not combine Esso-NS with other NSAIDs unless specifically advised.
• Tell your doctor about blood thinners, corticosteroids, aspirin, diuretics, or other medicines you take.
• Long-term NSAID treatment may increase the risk of gastrointestinal bleeding and cardiovascular or kidney problems.
• Esomeprazole reduces stomach acid but does not completely eliminate the risk of NSAID-related bleeding or ulcers.
• Avoid excessive alcohol because it can increase stomach irritation and bleeding risk.
• Consult your doctor before use during pregnancy or breastfeeding. NSAIDs should generally be avoided during the later stages of pregnancy.

FAQs

Q1: What is Esso-NS 375/20 Tablet used for?

Esso-NS contains naproxen sodium and esomeprazole and is used to help manage pain and inflammation while providing acid suppression to reduce some NSAID-related stomach risks.

Q2: How does Esso-NS 375/20 work?

Naproxen sodium reduces substances involved in pain and inflammation, while esomeprazole decreases stomach-acid production.

Q3: Can Esso-NS be used for arthritis?

Yes. The naproxen component may help relieve pain, swelling, and stiffness associated with conditions such as osteoarthritis and rheumatoid arthritis when prescribed.

Q4: Should Esso-NS be taken with food?

Follow your doctor's instructions. Taking the medicine with or after food may help reduce stomach discomfort, although the exact timing can depend on the formulation and treatment plan.

Q5: Can Esso-NS be taken with ibuprofen or diclofenac?

Do not combine it with other NSAIDs such as ibuprofen or diclofenac unless specifically instructed by your doctor, as this can increase the risk of stomach, kidney, and cardiovascular side effects.

Q6: Does esomeprazole completely protect the stomach from naproxen?

No. Esomeprazole can reduce stomach-acid-related risks, but it does not completely prevent ulcers or gastrointestinal bleeding caused by NSAIDs. Report any signs of bleeding promptly.