Ertugliflozin is an SGLT2 inhibitor that helps the kidneys remove excess glucose through urine. Sitagliptin is a DPP-4 inhibitor that increases incretin activity, supporting insulin release when blood glucose is elevated and reducing glucagon production. Together, these medicines provide complementary blood sugar-lowering effects.

Uses

• Helps control blood sugar in adults with type 2 diabetes
• Used alongside a healthy diet and regular exercise
• Helps increase urinary excretion of excess glucose
• Supports insulin release when blood glucose is elevated
• Helps reduce excessive glucagon production
• May be used when combination therapy with ertugliflozin and sitagliptin is appropriate

Benefits

• Combines two diabetes medicines with complementary mechanisms
• Helps lower elevated blood glucose levels
• Supports improved glycemic control
• May contribute to weight reduction in some patients
• Convenient once-daily oral formulation
• SGLT2 inhibition may provide cardiovascular and kidney benefits in appropriate patients

Dosage

• Take Ertahil SIT 5mg/100mg exactly as prescribed by your doctor.
• It is generally taken once daily, with or without food.
• Swallow the tablet whole with water.
• Maintain adequate fluid intake unless your doctor has advised fluid restriction.
• Your doctor may adjust treatment based on kidney function, blood glucose control, and other medicines you take.
• Do not change the dose or stop treatment without medical advice.
• If surgery or prolonged fasting is planned, tell your healthcare professional because temporary interruption may be recommended.

Possible Side Effects

Some people may experience:

• Increased urination
• Increased thirst
• Urinary tract infections
• Genital yeast infections
• Headache
• Nausea or diarrhea
• Upper respiratory symptoms
• Dizziness or low blood pressure

Rare but serious complications may include diabetic ketoacidosis, pancreatitis, acute kidney problems, severe dehydration, serious genital infections, and severe allergic reactions. Seek urgent medical attention for persistent vomiting, abdominal pain, difficulty breathing, confusion, severe weakness, facial swelling, or a severe rash.

Precautions

• Inform your doctor if you have kidney disease, liver disease, heart problems, recurrent urinary or genital infections, or a history of pancreatitis.
• Ertugliflozin can increase fluid loss and may cause dehydration or low blood pressure.
• Kidney function should be assessed before and during treatment as recommended by your doctor.
• Tell your doctor about all medicines you take, particularly insulin or insulin-releasing medicines, because the risk of hypoglycemia may increase when used together.
• Seek medical advice promptly if you develop symptoms suggestive of pancreatitis, such as persistent severe abdominal pain.
• Do not use in patients with severe renal impairment, end-stage kidney disease, or dialysis unless specifically directed by a specialist.
• Ertahil SIT is intended for type 2 diabetes and should not replace insulin treatment for type 1 diabetes.

FAQs

Q1: What is Ertahil SIT 5mg/100mg Tablet used for?

Ertahil SIT contains ertugliflozin 5mg and sitagliptin 100mg and is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Q2: How does Ertahil SIT 5mg/100mg work?

Ertugliflozin helps the kidneys remove excess glucose through urine, while sitagliptin increases incretin activity to support insulin release and reduce glucagon when blood glucose is elevated.

Q3: How often should Ertahil SIT 5mg/100mg be taken?

It is generally taken once daily, with or without food, but the exact regimen should be determined by your doctor.

Q4: Can Ertahil SIT cause increased urination?

Yes. Ertugliflozin increases urinary glucose excretion, which can lead to increased urination and thirst.

Q5: Can Ertahil SIT cause low blood sugar?

The combination has a relatively low risk of hypoglycemia when used alone, but the risk can increase when it is taken with insulin or insulin secretagogues.

Q6: Can Ertahil SIT be used for type 1 diabetes?

No. Ertahil SIT is indicated for adults with type 2 diabetes and should not be used as a replacement for insulin in type 1 diabetes.