Engerix-B Injection 20mcg 1PFS is a recombinant Hepatitis B vaccine designed to provide active immunization against infection caused by the Hepatitis B virus (HBV). The vaccine contains purified Hepatitis B surface antigen (HBsAg) produced using recombinant DNA technology and helps the body develop protective antibodies against the virus. It is indicated for adults aged 20 years and older and is supplied as a 1ml prefilled syringe (PFS) containing 20mcg of antigen.

Hepatitis B is a serious viral infection that affects the liver and can lead to chronic liver disease, cirrhosis, and liver cancer. Vaccination with Engerix-B is an effective way to prevent Hepatitis B infection and its complications.

Uses of Engerix-B Injection 20mcg 1PFS

• Prevention of Hepatitis B virus (HBV) infection
• Immunization of adults at risk of Hepatitis B exposure
• Protection for healthcare workers and medical students
• Vaccination for travelers visiting regions with high Hepatitis B prevalence
• Prevention of chronic liver disease associated with Hepatitis B infection

Benefits of Engerix-B Injection 20mcg 1PFS

• Provides protection against all known subtypes of Hepatitis B virus
• Helps develop long-lasting immunity
• Reduces the risk of chronic Hepatitis B infection
• Helps prevent liver cirrhosis and liver cancer related to HBV
• Well-established safety and efficacy profile
• Suitable for routine and high-risk adult vaccination programs

Dosage & Administration

• Administered by a healthcare professional as an intramuscular injection.
• Adults aged 20 years and older typically receive three doses of 1ml (20mcg) on a 0, 1, and 6-month schedule.
• Follow the vaccination schedule recommended by your healthcare provider.

Prescription Required: Yes

How It Works

Engerix-B contains a non-infectious Hepatitis B surface antigen that stimulates the immune system to produce protective antibodies. These antibodies help protect against future Hepatitis B virus infection without causing the disease itself.

Common Side Effects

Some individuals may experience:

• Pain, redness, or swelling at the injection site
• Headache
• Fatigue
• Mild fever
• Muscle aches
• Irritability
• Nausea

Most side effects are mild and temporary.

Do Not Use If

• You are allergic to Hepatitis B vaccine or any component of the vaccine
• You experienced a severe allergic reaction after a previous Hepatitis B vaccination
• You have a severe acute illness with fever (vaccination may be postponed)
• A healthcare professional advises against vaccination

Storage Instructions

• Store in a refrigerator at 2°C–8°C.
• Do not freeze.
• Keep the vaccine in its original packaging to protect it from light.
• Keep out of reach of children.

Frequently Asked Questions (FAQs)

Q1: What is Engerix-B Injection 20mcg 1PFS used for?

It is used to prevent Hepatitis B virus infection and its associated liver complications.

Q2: How many doses of Engerix-B are required for adults?

Adults generally require three doses administered at 0, 1, and 6 months.

Q3: Can Engerix-B cause side effects?

Yes, mild side effects such as injection-site pain, headache, fatigue, fever, and muscle aches may occur.

Q4: Does Engerix-B protect against other forms of hepatitis?

No. Engerix-B specifically protects against Hepatitis B and does not prevent Hepatitis A, C, D, or E infections.

Q5: Is a prescription required for Engerix-B Injection 20mcg 1PFS?