Empaglimet 12.5mg/1000mg Tablet is a combination medicine containing empagliflozin 12.5mg + metformin 1000mg. It is used along with diet and exercise to improve blood glucose control in adults with type 2 diabetes mellitus.

Empagliflozin belongs to the SGLT2 inhibitor class and helps the kidneys remove excess glucose through urine. Metformin belongs to the biguanide class and helps reduce glucose production by the liver while improving the body's sensitivity to insulin. Together, these medicines provide complementary blood-sugar-lowering effects.

Uses

• Management of type 2 diabetes
• Helps lower and control blood glucose levels
• Used with diet and exercise
• May provide cardiovascular benefits through empagliflozin in appropriate patients
• May help reduce the risk of certain diabetes-related complications in eligible patients

Benefits

• Combines two medicines with different mechanisms of action
• Helps improve blood glucose control
• Empagliflozin promotes urinary glucose elimination
• Metformin helps reduce excess glucose production by the liver
• May provide heart and kidney benefits in appropriate patients

Dosage

• Take Empaglimet exactly as prescribed by your doctor.
• The appropriate dose depends on your blood glucose control, kidney function, previous diabetes treatment, and tolerance.
• Because the tablet contains 1000mg of metformin, it is generally taken with meals to reduce stomach-related side effects.
• Swallow the tablet whole with water unless your specific product instructions say otherwise.
• Do not crush or split the tablet unless your pharmacist confirms that your formulation permits it.
• Maintain adequate fluid intake unless your doctor has advised fluid restriction.

Possible Side Effects

Common side effects may include:

• Nausea
• Diarrhea
• Stomach discomfort
• Increased urination
• Increased thirst
• Genital fungal infections
• Urinary tract infections

Rare but serious complications include lactic acidosis associated with metformin and diabetic ketoacidosis associated with empagliflozin. Seek urgent medical attention for severe weakness, persistent vomiting, abdominal pain, difficulty breathing, confusion, or unusual sleepiness.

Precautions

• Tell your doctor if you have kidney or liver disease, heart failure, recurrent urinary/genital infections, or a history of ketoacidosis.
• Kidney function should be assessed before and during treatment as appropriate.
• Avoid excessive alcohol consumption because it can increase the risk of metformin-associated lactic acidosis.
• Empagliflozin may cause dehydration and low blood pressure, particularly in people taking diuretics.
• Inform your doctor before surgery or prolonged fasting; empagliflozin may need to be temporarily discontinued.
• Tell your doctor if you are pregnant or breastfeeding.
• Empagliflozin/metformin is not intended for the treatment of type 1 diabetes.

FAQs

Q1: What is Empaglimet 12.5mg/1000mg Tablet used for?

It is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Q2: What are the ingredients in Empaglimet?

Each tablet contains empagliflozin 12.5mg and metformin 1000mg.

Q3: Should Empaglimet be taken with food?

Yes. Because it contains metformin, taking it with a meal can help reduce gastrointestinal side effects.

Q4: Can Empaglimet cause low blood sugar?

Empagliflozin and metformin alone have a relatively low risk of hypoglycemia. However, the risk can increase when they are combined with insulin or medicines such as sulfonylureas.

Q5: Can Empaglimet cause increased urination?

Yes. Empagliflozin increases glucose and water excretion through the urine, which can lead to increased urination and thirst.