Dapa-Met XR 5mg/1000mg Tablet is a combination diabetes medicine containing dapagliflozin 5mg and metformin hydrochloride 1000mg. It is used alongside diet and exercise to improve blood glucose control in adults with type 2 diabetes.

Dapagliflozin belongs to the SGLT2 inhibitor class and helps the kidneys remove excess glucose through urine. Metformin reduces glucose production by the liver and improves the body's response to insulin. Together, they provide complementary blood sugar-lowering effects.

The XR (extended-release) formulation allows metformin to be released gradually. Follow the product instructions and swallow the tablet whole unless your specific product labeling states otherwise.

Uses

• Helps control blood sugar in adults with type 2 diabetes
• Used alongside a healthy diet and regular exercise
• Helps reduce glucose production by the liver
• Promotes removal of excess glucose through urine
• May provide cardiovascular and kidney benefits in appropriate patients

Benefits

• Helps lower elevated blood glucose levels
• Combines dapagliflozin and metformin in one tablet
• May support modest weight reduction in some patients
• Dapagliflozin may provide cardiovascular and kidney benefits in appropriate patients
• Convenient extended-release formulation

Dosage

• Take Dapa-Met XR 5mg/1000mg exactly as prescribed by your doctor.
• It is generally taken once daily with a meal, according to the prescribed regimen.
• Swallow the extended-release tablet whole with water. Do not crush, chew, or split it unless your product instructions specifically permit this.
• Maintain adequate fluid intake unless your doctor has advised fluid restriction.
• Your doctor may adjust the dose based on blood glucose control, kidney function, and tolerance.
• Do not change the dose or stop treatment without medical advice.

Possible Side Effects

Some people may experience:

• Increased urination
• Increased thirst
• Nausea
• Diarrhea
• Stomach discomfort
• Headache
• Genital yeast infections
• Urinary tract infections

Rare but serious complications include lactic acidosis associated with metformin and diabetic ketoacidosis associated with SGLT2 inhibitors. Seek urgent medical attention for severe weakness, persistent vomiting, abdominal pain, difficulty breathing, confusion, or unusual drowsiness.

Precautions

• Inform your doctor if you have kidney disease, liver disease, heart failure, dehydration, or recurrent urinary or genital infections.
• Kidney function should be assessed before and during treatment as recommended by your doctor.
• Dapagliflozin can increase fluid loss and may cause dehydration or low blood pressure.
• Follow your healthcare professional's instructions about temporarily stopping the medicine during serious illness, prolonged fasting, or before certain surgical procedures.
• Metformin may need to be temporarily withheld around certain iodinated contrast imaging procedures.
• Tell your doctor about all medicines and supplements you take.
• Dapa-Met XR is not intended for the treatment of type 1 diabetes.

FAQs

Q1: What is Dapa-Met XR 5mg/1000mg Tablet used for?

Dapa-Met XR contains dapagliflozin 5mg and metformin 1000mg and is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Q2: How does Dapa-Met XR 5mg/1000mg work?

Dapagliflozin helps the kidneys remove excess glucose through urine, while metformin reduces glucose production by the liver and improves insulin sensitivity.

Q3: Should Dapa-Met XR be taken with food?

Yes. The metformin extended-release component is generally taken with a meal to improve gastrointestinal tolerance. Follow your doctor's instructions.

Q4: Can Dapa-Met XR cause increased urination?

Yes. Dapagliflozin increases glucose excretion through urine, which can result in more frequent urination and increased thirst.

Q5: Can Dapa-Met XR cause low blood sugar?

The combination has a relatively low risk of hypoglycemia when used alone. The risk may increase when it is combined with insulin or sulfonylureas.

Q6: Can Dapa-Met XR be used for type 1 diabetes?

No. Dapa-Met XR is intended for type 2 diabetes and should not replace insulin therapy in people with type 1 diabetes.