Dapa Met XR 10/1000mg Tablet is a combination medicine containing dapagliflozin 10mg and metformin hydrochloride 1000mg. It is used along with diet and exercise to improve blood glucose control in adults with type 2 diabetes.

Dapagliflozin is an SGLT2 inhibitor that helps the kidneys remove excess glucose from the body through urine. Metformin helps reduce glucose production by the liver and improves the body's sensitivity to insulin. Together, these medicines provide complementary blood sugar-lowering effects.

The XR (extended-release) formulation is designed to release metformin gradually. Swallow the tablet whole and follow your doctor's instructions.

Uses

• Helps control blood sugar in adults with type 2 diabetes
• Used alongside a healthy diet and regular exercise
• Helps reduce glucose production by the liver
• Promotes urinary excretion of excess glucose
• May provide additional cardiovascular or kidney benefits in appropriate patients

Benefits

• Helps lower elevated blood glucose levels
• Combines two complementary diabetes medicines in one tablet
• May support weight reduction in some patients
• Dapagliflozin may provide cardiovascular and kidney benefits in appropriate patients
• Convenient extended-release tablet formulation

Dosage

• Take Dapa Met XR 10/1000mg exactly as prescribed by your doctor.
• It is usually taken once daily with food, according to the prescribed regimen.
• Swallow the extended-release tablet whole with water. Do not crush, split, or chew it unless your product information specifically permits this.
• Maintain adequate fluid intake unless your doctor has advised fluid restriction.
• Your doctor may adjust the dose according to blood glucose control and kidney function.
• Do not change the dose or stop treatment without medical advice.

Possible Side Effects

Some people may experience:

• Increased urination
• Thirst
• Nausea
• Diarrhea
• Stomach discomfort
• Headache
• Genital yeast infections
• Urinary tract infections

Rare but serious complications include lactic acidosis associated with metformin and diabetic ketoacidosis associated with SGLT2 inhibitors. Seek urgent medical attention for severe weakness, persistent vomiting, abdominal pain, difficulty breathing, confusion, or unusual drowsiness.

Precautions

• Inform your doctor if you have kidney disease, liver disease, heart failure, dehydration, or a history of recurrent urinary or genital infections.
• Kidney function should be assessed before and during treatment as recommended by your doctor.
• Dapagliflozin can cause dehydration and low blood pressure, particularly in people taking diuretics or those who do not drink enough fluids.
• Follow your healthcare professional's instructions about temporarily stopping the medicine during serious illness, prolonged fasting, or before certain surgical procedures.
• Metformin should generally be withheld around certain iodinated contrast imaging procedures when clinically indicated.
• Tell your doctor about all medicines you take, including diuretics and other diabetes medicines.
• Dapa Met XR is not intended to treat type 1 diabetes.

FAQs

Q1: What is Dapa Met XR 10/1000mg Tablet used for?

Dapa Met XR contains dapagliflozin and metformin and is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes.

Q2: How does Dapa Met XR 10/1000mg work?

Dapagliflozin helps the kidneys remove excess glucose through urine, while metformin reduces glucose production by the liver and improves insulin sensitivity.

Q3: Should Dapa Met XR be taken with food?

Yes. The metformin extended-release component is generally taken with food to improve gastrointestinal tolerance. Follow your doctor's instructions.

Q4: Can Dapa Met XR cause increased urination?

Yes. Dapagliflozin increases glucose excretion through urine, which can result in more frequent urination and increased thirst.

Q5: Can Dapa Met XR cause low blood sugar?

The combination has a relatively low risk of hypoglycemia when used alone, but the risk can increase when it is combined with insulin or medicines such as sulfonylureas.

Q6: Can Dapa Met XR be used for type 1 diabetes?

No. Dapa Met XR is intended for type 2 diabetes and should not be used as a substitute for insulin therapy in type 1 diabetes.