Crestat EZ 20/10mg Tablet combines rosuvastatin 20mg and ezetimibe 10mg, two powerful cholesterol‑lowering agents used to manage high cholesterol (hyperlipidemia) and reduce the risk of cardiovascular disease. Rosuvastatin is a statin that blocks cholesterol production in the liver, while ezetimibe reduces absorption of cholesterol from the intestine — together they provide stronger lipid control than either alone. This combination is especially beneficial for patients who cannot achieve target lipid levels with statin therapy alone, and it supports long‑term heart health when used under medical supervision.

Price in Pakistan

The approximate price of Crestat EZ 20/10mg Tablet in Pakistan ranges between Rs. 2,200 – Rs. 2,800 per strip (10 tablets), depending on the pharmacy and location.

Uses

• Lowers total cholesterol and LDL (“bad” cholesterol)

• Helps raise HDL (“good” cholesterol)

• Reduces triglycerides

• Supports prevention of heart attack and stroke risk

• Used when statin alone is insufficient

Benefits

• Dual‑action lipid reduction

• Improves overall cholesterol profile

• Can help achieve target lipid goals faster

• Supports long‑term cardiovascular health

• Convenient once‑daily tablet

Prescription Required: Yes

Generic Name: Rosuvastatin + Ezetimibe

Use: Cholesterol and cardiovascular risk management

How It Works

Crestat EZ Tablet combines two mechanisms: rosuvastatin inhibits HMG‑CoA reductase — the enzyme the liver uses for cholesterol production — reducing internal cholesterol levels; ezetimibe blocks absorption of dietary and biliary cholesterol in the intestine. The combined effect significantly lowers LDL cholesterol and helps improve overall lipid profile.

Dosage

• Take as prescribed by your doctor

• Usually 1 tablet once daily, with or without food

• Take at the same time each day for consistency

• Do not crush or chew the tablet

• Regular lipid profile monitoring is recommended

Common Side Effects

• Muscle pain or weakness

• Headache

• Stomach discomfort

• Elevated liver enzymes

• Rare: muscle breakdown (myopathy)

Drug Interactions

• May interact with fibrates or certain antivirals

• Caution with other cholesterol‑lowering agents

• Inform your doctor about all current medications

Do Not Use If

• Allergy to rosuvastatin, ezetimibe, or statins

• Active liver disease or unexplained persistent liver enzyme elevations

• Pregnancy or breastfeeding without doctor advice

• Severe kidney impairment without medical supervision

Storage

Store at room temperature, away from moisture and sunlight. Keep tablets in original packaging and out of reach of children.

FAQs

Q1: What is Crestat EZ Tablet 20/10mg used for?

It’s used to lower LDL cholesterol and improve overall lipid profile in adults.

Q2: How often should it be taken?

Usually once daily, as prescribed by your doctor.

Q3: Can it be taken with food?

Yes, it can be taken with or without food.

Q4: Is a prescription required?

Yes, medical supervision and a prescription are required.

Q5: Does it cause muscle pain?

Some patients may experience muscle pain, which should be reported to a doctor.

Q6: Is regular blood testing needed?

Yes, liver and lipid levels should be monitored regularly.

Q7: Can it reduce heart attack/stroke risk?

Yes, by improving cholesterol levels, it supports cardiovascular risk reduction.

Q8: Can it be used long‑term?

Yes, long‑term use is common under medical guidance for chronic cholesterol management.