Perindopril is an ACE inhibitor that helps relax blood vessels by reducing the effects of angiotensin II. Amlodipine is a calcium channel blocker that relaxes and widens blood vessels. Together, they help lower blood pressure and reduce the workload on the heart.

Uses

• Helps control high blood pressure
• Used when combination antihypertensive treatment is appropriate
• Helps relax and widen blood vessels
• Reduces resistance to blood flow
• Helps reduce strain on the heart and blood vessels
• May help lower the risk of cardiovascular complications associated with uncontrolled hypertension

Benefits

• Combines perindopril and amlodipine in one tablet
• Provides complementary blood-pressure-lowering effects
• Helps maintain better blood pressure control
• Reduces strain on the cardiovascular system
• Convenient once-daily tablet formulation
• May simplify treatment for patients requiring both medicines

Dosage

• Take Coversam 4mg/5mg exactly as prescribed by your doctor.
• It is generally taken once daily, preferably in the morning before a meal.
• Swallow the tablet with water.
• Take it at approximately the same time each day.
• Your doctor may adjust treatment according to blood pressure response and tolerance.
• Do not change the dose or stop treatment without medical advice.

Possible Side Effects

Some people may experience:

• Dizziness or lightheadedness
• Headache
• Ankle or leg swelling
• Flushing
• Fatigue
• Dry cough
• Nausea
• Low blood pressure

Rarely, serious reactions such as angioedema, kidney problems, or abnormal potassium levels may occur. Seek urgent medical attention for swelling of the face, lips, tongue, or throat, difficulty breathing, fainting, or severe weakness.

Precautions

• Tell your doctor if you have kidney disease, liver disease, heart problems, low blood pressure, or high potassium levels.
• Your doctor may monitor blood pressure, kidney function, and potassium levels during treatment.
• Avoid potassium supplements or potassium-containing salt substitutes unless specifically recommended by your healthcare professional.
• Inform your doctor if you develop a persistent dry cough or significant swelling.
• Perindopril should not be used during pregnancy, as ACE inhibitors can harm the developing baby.
• Tell your doctor about all medicines, vitamins, and supplements you take.
• Rise slowly from sitting or lying down if you experience dizziness.
• Do not stop treatment without consulting your doctor.

FAQs

Q1: What is Coversam 4mg/5mg Tablet used for?

Coversam contains perindopril 4mg and amlodipine 5mg and is used to help control high blood pressure.

Q2: How does Coversam 4mg/5mg work?

Perindopril relaxes blood vessels by inhibiting the ACE pathway, while amlodipine relaxes blood vessels by blocking calcium channels. Together, they help lower blood pressure.

Q3: Should Coversam be taken with food?

Coversam is generally taken once daily before a meal, according to the prescribing information. Follow your doctor's instructions.

Q4: Can Coversam cause ankle swelling?

Yes. Amlodipine may cause ankle or leg swelling. Inform your doctor if swelling is persistent, severe, or accompanied by breathing difficulty.

Q5: Can Coversam be taken during pregnancy?

No. Perindopril can harm the developing baby and should not be used during pregnancy. Contact your doctor immediately if you become pregnant while taking Coversam.

Q6: Can Coversam cause a dry cough?

Yes. Perindopril and other ACE inhibitors can cause a persistent dry cough in some people. Speak with your doctor if this occurs.