Cilenem 500mg Injection is a prescription antibiotic containing Imipenem 500mg and Cilastatin 500mg. It belongs to the carbapenem class of antibiotics and is used to treat a wide range of serious bacterial infections.

Imipenem kills susceptible bacteria by preventing the formation of their protective cell wall, while Cilastatin prevents the breakdown of Imipenem in the kidneys, allowing it to remain effective for a longer period. Cilenem is commonly administered in hospitals for severe infections and should only be used under the supervision of a qualified healthcare professional.

Uses

• Treatment of severe bacterial infections
• Lower respiratory tract infections (including pneumonia)
• Complicated urinary tract infections (UTIs)
• Intra-abdominal infections
• Skin and soft tissue infections
• Bone and joint infections
• Bloodstream infections (septicemia)
• Gynecological infections caused by susceptible bacteria

Benefits

• Broad-spectrum antibiotic effective against many bacteria
• Helps treat serious and life-threatening infections
• Rapid antibacterial action
• Effective against mixed bacterial infections
• Suitable for hospital management of complicated infections

Dosage

• Administer only by a qualified healthcare professional.
• Given by intravenous (IV) infusion as prescribed by your doctor.
• The dosage depends on the type and severity of the infection, kidney function, age, and body weight.
• Complete the full course of treatment even if symptoms improve earlier.

Prescription Required: Yes.

How It Works

Imipenem destroys bacteria by inhibiting bacterial cell wall synthesis, leading to bacterial death. Cilastatin inhibits the renal enzyme that breaks down Imipenem, increasing its effectiveness and maintaining adequate antibiotic levels in the body.

Common Side Effects

• Nausea
• Vomiting
• Diarrhea
• Headache
• Skin rash
• Injection site pain or inflammation
• Dizziness
• Elevated liver enzymes

Seek immediate medical attention if you experience severe allergic reactions, persistent diarrhea, seizures, or difficulty breathing.

Do Not Use If

• You are allergic to Imipenem, Cilastatin, other carbapenem antibiotics, or any ingredient in the injection.
• You have experienced severe allergic reactions to beta-lactam antibiotics unless advised by your doctor.
• The medicine has not been prescribed by a qualified healthcare professional.
• Use with caution in patients with kidney disease or a history of seizures, as directed by a healthcare provider.

Storage Instructions

• Store below 25°C.
• Protect from heat, light, and moisture.
• Do not freeze.
• Keep out of the reach of children.

Price in Pakistan

The price of Cilenem 500mg Injection (1 vial) in Pakistan generally ranges from Rs. 1,150 to Rs. 1,350 per vial, depending on the pharmacy and location.

Frequently Asked Questions (FAQs)

Q1: What is Cilenem 500mg Injection used for?

Cilenem 500mg Injection is used to treat severe bacterial infections, including pneumonia, urinary tract infections, intra-abdominal infections, skin infections, bone infections, and bloodstream infections.

Q2: How is Cilenem 500mg Injection administered?

It is administered by intravenous (IV) infusion by a qualified healthcare professional in a hospital or clinical setting.

Q3: Can Cilenem 500mg Injection treat viral infections?

No. Cilenem is effective only against bacterial infections and does not treat viral illnesses such as the common cold or influenza.

Q4: What should I do if I miss a dose?

Since this medicine is usually administered in a healthcare facility, missed doses are uncommon. If a dose is missed, your healthcare provider will determine the appropriate schedule.

Q5: Is a prescription required for Cilenem 500mg Injection?

Yes. Cilenem 500mg Injection is a prescription-only antibiotic and should only be used under the supervision of a qualified healthcare professional.