What is Upadacitinib?
Upadacitinib is an oral Janus kinase (JAK) inhibitor used to treat moderate to severe inflammatory and autoimmune diseases. It works by reducing abnormal immune activity that causes inflammation, pain, and joint damage.
Upadacitinib is commonly prescribed when patients do not respond adequately to conventional therapies.
Uses of Upadacitinib
Upadacitinib is used in the treatment of:
- Rheumatoid arthritis
- Psoriatic arthritis
- Ankylosing spondylitis
- Atopic dermatitis (eczema)
- Other immune-mediated inflammatory disorders (as prescribed)
It helps reduce joint pain, swelling, stiffness, skin inflammation, and improves quality of life.
Mechanism of Action
Upadacitinib selectively inhibits JAK-1 enzymes, which play a key role in immune signaling pathways. By blocking these pathways, it:
- Reduces inflammatory cytokine production
- Suppresses overactive immune responses
- Controls inflammation and disease progression
This targeted action helps manage symptoms while limiting widespread immune suppression.
Dosage & Administration
- Commonly prescribed dose: 15mg once daily
- Can be taken with or without food
- Swallow tablet whole; do not crush or chew
- Dosage may vary based on condition and patient response
Always follow your doctor’s instructions.
Drug Interactions
Use caution when taking Upadacitinib with:
- Strong immunosuppressants
- Live vaccines (avoid during treatment)
- Certain antifungal or antiviral medicines
- Other JAK inhibitors or biologics
Always inform your doctor about all medicines and supplements you are using.
Side Effects
Common side effects may include:
- Upper respiratory infections
- Nausea
- Headache
- Increased cholesterol levels
Serious but less common risks include infections, blood clots, and liver enzyme changes. Regular monitoring is recommended.
Precautions
- Increased risk of infections; report fever or symptoms immediately
- Not recommended during pregnancy or breastfeeding
- Regular blood tests may be required
- Use cautiously in patients with liver disease or history of blood clots
Available Brands of Upadacitinib in Pakistan
The following Upadacitinib 15mg tablets are available:
- Upacent 15mg Tablet
- Upaget XR 15mg Tablet
Both brands contain the same active ingredient and are used according to medical advice.
Frequently Asked Questions (FAQs)
Q1: What is Upadacitinib used for?
It is used to treat autoimmune and inflammatory conditions such as rheumatoid arthritis and eczema.
Q2: How long does Upadacitinib take to work?
Some patients notice improvement within a few weeks, while full benefits may take longer.
Q3: Is Upadacitinib a steroid?
No, it is not a steroid. It is a JAK inhibitor that targets immune pathways.
Q4: Can Upadacitinib be taken daily?
Yes, it is usually taken once daily as prescribed.
Q5: Do I need tests while using Upadacitinib?
Yes, regular blood tests are recommended to monitor safety.
Q6: Can vaccines be taken during treatment?
Live vaccines should be avoided. Consult your doctor before vaccination.
Why Buy Upadacitinib from Mr Medicine Mart?
✔ 100% genuine & pharmacy-verified medicines
✔ Availability of Upacent 15mg & Upaget 15mg Tablets
✔ Proper storage and handling standards
✔ Fast and reliable delivery across Pakistan
✔ Trusted online pharmacy with professional support
Upadacitinib tablets (Upacent 15mg & Upaget 15mg) are available at Mr Medicine Mart, ensuring authentic products, safe handling, and dependable service.