Sevelamer is a commonly prescribed phosphate binder used in patients with chronic kidney disease (CKD), especially those on dialysis. It helps control high phosphate levels in the blood, which can otherwise lead to serious complications like bone disorders and heart problems.
In Pakistan, Sevelamer is available under multiple brand names including:
All of these contain the same active ingredient: Sevelamer.
What is Sevelamer?
Sevelamer is a phosphate-binding medication used primarily in patients suffering from chronic kidney disease (CKD), particularly those undergoing dialysis. When kidneys fail to remove excess phosphorus from the blood, phosphate levels increase — leading to complications such as:
- Weak bones (renal osteodystrophy)
- Vascular calcification
- Cardiovascular disease
- Itching and skin problems
Sevelamer helps reduce phosphate absorption from food.
Uses of Sevelamer
Sevelamer is used for:
1. Hyperphosphatemia (High Phosphate Levels)
Especially in patients with:
- Chronic Kidney Disease (CKD)
- End-Stage Renal Disease (ESRD)
- Patients on hemodialysis or peritoneal dialysis
2. Preventing Bone & Heart Complications
By lowering phosphate levels, it reduces:
- Bone weakening
- Calcium deposits in blood vessels
- Risk of heart disease
How Sevelamer Works
Sevelamer is a non-calcium, non-metal phosphate binder.
- It works in the intestine
- Binds dietary phosphate from food
- Prevents its absorption into the bloodstream
- Phosphate is then eliminated through stool
It does not get absorbed into the bloodstream, which makes it safer for long-term use.
Dosage
Always use as prescribed by your nephrologist.
General Adult Dosage:
- Usually taken 3 times daily with meals
- Dose depends on blood phosphate levels
- Typical starting dose: 800mg to 1600mg per meal
Important Instructions:
- Take with food
- Swallow tablet whole (do not crush unless doctor allows)
- Regular blood tests are required to monitor phosphate levels
Side Effects
Like all medicines, Sevelamer may cause some side effects.
Common Side Effects:
- Nausea
- Vomiting
- Constipation
- Diarrhea
- Stomach pain
- Bloating
Serious Side Effects:
- Severe abdominal pain
- Intestinal blockage
- Difficulty swallowing
If severe symptoms occur, consult your doctor immediately.
Drug Interactions
Sevelamer may interfere with absorption of certain medicines:
- Levothyroxine
- Ciprofloxacin
- Mycophenolate
- Anti-epileptic drugs
It is usually advised to take other medicines 1 hour before or 3 hours after Sevelamer.
Who Should Not Use Sevelamer?
Do not use if you have:
- Low phosphate levels (hypophosphatemia)
- Bowel obstruction
- Severe swallowing problems
Always inform your doctor about your full medical history.
Available Sevelamer Brands in Pakistan
Sevelamer is available in Pakistan under the following brands:
All contain Sevelamer and are prescribed for phosphate control in CKD patients.
You can check availability and home delivery options at Mr Medicine Mart, one of Pakistan’s trusted online pharmacies offering genuine medicines at competitive prices.
Frequently Asked Questions (FAQs)
Q1: What is Sevelamer used for?
Sevelamer is used to control high phosphate levels in patients with chronic kidney disease, especially those on dialysis.
Q2: Is Sevelamer safe for long-term use?
Yes, it is commonly prescribed for long-term use under medical supervision with regular blood monitoring.
Q3: Can Sevelamer increase calcium levels?
No. Unlike some other phosphate binders, Sevelamer does not contain calcium and does not raise calcium levels.
Q4: When should I take Sevelamer?
It should be taken with meals to effectively bind dietary phosphate.
Q5: Is Sevelamer available in Pakistan?
Yes, Sevelamer is available in Pakistan under brands like SEVLA Tablet, SVL Tablet, RENAVEL Tablet, SEVELAWIN Tablet, and SELCARB Tablet.
You can order it from Mr Medicine Mart with home delivery available at best prices across Pakistan.
Final Words
Managing phosphate levels is extremely important for kidney patients. Sevelamer plays a crucial role in preventing bone disease and heart complications associated with high phosphate levels.
Always consult a qualified healthcare provider before starting or adjusting this medication. For genuine medicines and convenient delivery in Pakistan, you can check availability at Mr Medicine Mart.