Pentasa contains Mesalazine (5-ASA), an anti-inflammatory medicine used to treat inflammatory bowel diseases (IBD) such as Ulcerative Colitis and Crohn’s disease. It works directly on the lining of the intestine to reduce inflammation, swelling, and irritation.
Pentasa is available in different forms including tablets, granules, and suppositories, depending on the location and severity of the disease.
What is Pentasa Used For?
Pentasa is mainly used for:
- Treating Ulcerative Colitis
- Managing Crohn’s Disease
- Reducing inflammation in the colon and intestines
- Maintaining remission (preventing flare-ups) in IBD patients
- Reducing abdominal pain, diarrhea, and blood in stools
Important: Pentasa does not cure IBD, but it helps control symptoms and prevent disease worsening.
How Pentasa Works
Mesalazine works by reducing inflammation in the lining of the intestine. It blocks the release of inflammatory chemicals, which helps heal the gut lining and relieve symptoms like diarrhea, pain, and bleeding.
Dosage
Dosage depends on the patient’s condition and severity of disease:
For Ulcerative Colitis:
- Mild to moderate disease: 1–2 g per day in divided doses
- Severe cases: Up to 4 g per day as prescribed
For Maintenance Therapy:
- Usually 1–2 g per day
Take with or without food as directed by your doctor. Do not crush or chew extended-release tablets unless advised.
Side Effects
Common side effects may include:
- Headache
- Nausea
- Abdominal pain
- Diarrhea
- Gas or bloating
Rare but serious side effects:
- Kidney problems
- Severe allergic reactions (rash, swelling, breathing difficulty)
- Blood disorders
If you notice severe symptoms, stop the medicine and consult a doctor immediately.
Who Should Avoid Pentasa?
Do not use Pentasa if:
- You are allergic to Mesalazine or salicylates
- You have severe kidney disease unless monitored
- You are pregnant or breastfeeding without doctor’s advice
Precautions & Warnings
- Regular kidney function tests may be required
- Inform your doctor if you have liver or kidney problems
- Do not stop medication suddenly without medical advice
Frequently Asked Questions (FAQs)
Q: What is Pentasa used for?
A: Pentasa is used to treat inflammatory bowel diseases such as Ulcerative Colitis and Crohn’s disease by reducing intestinal inflammation.
Q: Who can use Pentasa?
A: Patients diagnosed with Ulcerative Colitis or Crohn’s disease, as prescribed by a gastroenterologist.
Q: How to use Pentasa?
A: Take as directed by your doctor, usually in divided doses daily. Do not crush or chew extended-release tablets unless advised.
Q: Is Pentasa safe?
A: Yes, when used under medical supervision with regular monitoring, especially for kidney function.
Q: What are the side effects of Pentasa?
A: Common side effects include headache, nausea, abdominal pain, and diarrhea; rare serious effects may include kidney problems or allergic reactions.
Q: Are there alternatives to Pentasa?
A: Yes, alternatives include Asacol (Mesalazine), Salofalk, Sulfasalazine, Budesonide, and Steroids, depending on the case.
Q: Is Pentasa available in Pakistan?
A: Yes, Pentasa is available at Mr Medicine Mart in Pakistan, with home delivery and best prices.
Q: Where can I buy Pentasa in Pakistan?
A: You can purchase Pentasa from Mr Medicine Mart, which offers genuine medicines, competitive pricing, and reliable nationwide home delivery.