Hydrocortisone is a corticosteroid medicine used to reduce inflammation and suppress overactive immune responses. It is commonly prescribed for allergic reactions, autoimmune disorders, adrenal insufficiency, and certain inflammatory conditions.
In Pakistan, hydrocortisone tablets are available under different brand names including Corticort Tablet and Hydrocortisone Tablet formulations.
What Is Hydrocortisone?
Hydrocortisone is a synthetic version of cortisol, a hormone naturally produced by the adrenal glands. Cortisol plays an essential role in regulating metabolism, immune response, and the body’s stress response.
When the body does not produce enough cortisol — or when inflammation becomes excessive — hydrocortisone is prescribed to restore balance.
Uses of Hydrocortisone Tablets
Hydrocortisone tablets such as Corticort are used for:
- Adrenal insufficiency (Addison’s disease)
- Severe allergic reactions
- Asthma exacerbations
- Rheumatoid arthritis
- Lupus and autoimmune disorders
- Inflammatory bowel disease
- Skin and inflammatory conditions
- Certain blood disorders
It may also be used as part of hormone replacement therapy in adrenal gland disorders.
How Hydrocortisone Works
Hydrocortisone works by:
- Reducing inflammation
- Suppressing immune system overactivity
- Replacing deficient cortisol levels
- Controlling allergic and autoimmune reactions
It helps relieve symptoms like swelling, redness, pain, and immune-mediated tissue damage.
Dosage
Dosage depends on the condition being treated:
- Adrenal insufficiency: Typically divided doses throughout the day
- Inflammatory conditions: Varies depending on severity
- Acute allergic reactions: Short-term higher doses may be prescribed
Doctors usually prescribe the lowest effective dose for the shortest possible duration to minimize side effects.
Never stop hydrocortisone suddenly, especially after long-term use. Gradual tapering is required.
Side Effects
Hydrocortisone may cause:
- Increased appetite
- Weight gain
- Mood changes
- Insomnia
- Fluid retention
- Increased blood sugar levels
- Stomach irritation
Serious Side Effects
- Severe mood changes
- Vision problems
- High blood pressure
- Signs of infection
- Severe stomach pain
- Bone thinning with long-term use
Long-term corticosteroid therapy requires medical monitoring.
Warnings & Precautions
- Use cautiously in diabetes patients
- Not recommended in untreated infections
- Avoid live vaccines during therapy
- Inform your doctor if pregnant or breastfeeding
- Monitor blood pressure and blood sugar if on prolonged treatment
Frequently Asked Questions (FAQs)
Q: What is Hydrocortisone tablet used for?
A: It is used to treat adrenal insufficiency, allergies, autoimmune diseases, and inflammatory conditions.
Q: Is Corticort a steroid?
A: Yes, Corticort contains hydrocortisone, which is a corticosteroid.
Q: Can hydrocortisone cause weight gain?
A: Yes, especially with long-term use due to fluid retention and increased appetite.
Q: Can I stop hydrocortisone suddenly?
A: No. Sudden discontinuation may cause adrenal crisis. Always follow doctor’s tapering instructions.
Q: Is hydrocortisone safe for long-term use?
A: It can be used long-term under medical supervision, but regular monitoring is necessary to avoid complications.
Final Thoughts
Hydrocortisone tablets, including Corticort Tablet and other hydrocortisone formulations, are essential medicines for managing inflammation, allergies, and adrenal disorders. While highly effective, they must be used carefully under medical supervision to prevent side effects and complications.