Azathioprine is a prescription immunosuppressive medication used to treat a variety of autoimmune diseases and to prevent organ rejection after transplant. It works by reducing the activity of the immune system, helping control inflammation and preventing the body from attacking its own tissues.
Common brand names include Imuran, Azafrine, and Amorin.
What is Azathioprine Used For?
Azathioprine is commonly prescribed for:
- Rheumatoid arthritis
- Systemic lupus erythematosus (SLE)
- Inflammatory bowel disease (Crohn’s disease & ulcerative colitis)
- Autoimmune hepatitis
- Prevention of organ rejection after kidney transplant
It helps reduce inflammation, prevent disease progression, and control immune-related damage.
How Does Azathioprine Work?
Azathioprine belongs to a class of drugs called immunosuppressants. It reduces the production of white blood cells that are responsible for immune responses. By suppressing overactive immune function, it helps control autoimmune disorders and prevents transplant rejection.
Dosage
- The dosage depends on the medical condition, body weight, and response to treatment.
- For autoimmune diseases, doses usually range between 1–3 mg/kg per day.
- For transplant patients, higher doses may be prescribed initially.
Always take Azathioprine exactly as prescribed by your doctor. Do not adjust the dose without medical advice.
How to Take Azathioprine
- Take with food to reduce stomach upset.
- Swallow the tablet whole with water.
- Take at the same time daily for best results.
- Regular blood tests are required to monitor liver function and blood cell counts.
Side Effects
Like all medicines, Azathioprine may cause side effects.
Common Side Effects:
- Nausea and vomiting
- Loss of appetite
- Mild hair thinning
- Fatigue
Serious Side Effects:
- Increased risk of infections
- Low white blood cell count
- Liver problems
- Pancreatitis
- Increased risk of certain cancers (with long-term use)
Contact your doctor immediately if you experience fever, unusual bruising, yellowing of skin, or severe abdominal pain.
Warnings & Precautions
- Not recommended during pregnancy unless clearly advised by a doctor.
- Avoid live vaccines while taking this medication.
- Inform your doctor if you have liver disease or infections.
- Regular blood monitoring is essential.
Frequently Asked Questions (FAQs)
Q: What is Azathioprine used for?
A: It is used to treat autoimmune diseases such as rheumatoid arthritis, lupus, inflammatory bowel disease, and to prevent organ rejection after transplant.
Q: Who can use Azathioprine?
A: It can be used by adults and children under medical supervision for autoimmune conditions or after organ transplant. It must only be taken with a doctor’s prescription.
Q: How to use Azathioprine?
A: Take it exactly as prescribed, usually once daily with food. Regular blood tests are necessary during treatment.
Q: Is Azathioprine safe?
A: It is safe when used under medical supervision. However, it requires regular monitoring due to potential serious side effects.
Q: What are the side effects of Azathioprine?
A: Common side effects include nausea and fatigue. Serious risks include infections, liver issues, and low blood cell counts.
Q: Are there alternatives to Azathioprine?
A: Yes, alternatives may include methotrexate, mycophenolate mofetil, cyclosporine, or biologic therapies depending on the condition. Consult your doctor for suitable options.
Q: Is Azathioprine available in Pakistan?
A: Yes it's Available at Mr Medicine Mart in Pakistan, Home Delivery Available with Best Prices.
Q: Where can I buy Azathioprine in Pakistan?
A: You can buy it from licensed pharmacies across Pakistan or order online from Mr Medicine Mart with convenient home delivery services.